Sonophoresis
Ultrasound-driven transdermal delivery (low-frequency 20–100 kHz, high-frequency 0.7–3 MHz) for enhanced penetration of bioregulator compounds.
Ultrasound-driven transdermal delivery (low-frequency 20–100 kHz, high-frequency 0.7–3 MHz) for enhanced penetration of bioregulator compounds.
Full mechanistic definition forthcoming.
A documented format in pharmaceutical practice.
Historical timeline of the delivery format in the pharmaceutical literature — first characterization, commercial precedents, decades of regulatory-approved use — forthcoming.
How the format delivers.
Absorption pathway, bioavailability characteristics, first-pass metabolism considerations, onset and duration profiles — forthcoming.
Bioregulators formulated for this platform.
Bioregulator compounds formulated for ultrasound-enhanced transdermal delivery.
See the full bioregulator class and the per-compound published literature for compound-specific research references.
Classification and oversight.
OTC device classification; cosmetic (MoCRA) for compatible peptide formulations.
Detailed regulatory analysis — agency-specific requirements, classification thresholds, and pathway-specific labeling considerations — forthcoming.
The format in the scientific literature.
PubMed-indexed peer-reviewed references establishing the format as legitimate pharmaceutical science — forthcoming.
The Atumnus Sonogenix™ platform.
The Sonogenix™ platform is the Atumnus patent-pending embodiment of Sonophoresis. It is licensed to operating affiliates for commercial development across the Opticeutical and Endoceutical tiers, and is one of the branded delivery technologies that anchors the Atumnus intellectual-property estate.
The Sonogenix™ trademark and associated patent-pending technology are held by Atumnus LLC, the founding entity of endogenic pharmacology. See affiliated entities for institutional structure.
Adjacent delivery formats.
Within the same cluster (Topical and Transdermal Delivery), see the full set of delivery platforms in this category.